The ruler of Latovilia, Dr. Doom, fell into a fierce conflict with Dr. Doom from 2099 over the domination of the universe. This led to countless universes colliding and merging in the entanglement of time flow, giving rise to new worlds and crises.

Now, superheroes and villains from the multiverse gather together, either working together or fighting against each other, each striving to avoid making any Doctor Doom's domination a reality. Nowadays, once familiar faces have become enemies, while former enemies have become the strongest allies in this conflict